Oxytocin in Zebrafish Social Buffering

Anna Riordan '23 investigates the role of oxytocin in zebrafish social buffering.

Allentown, PA (12/08/2022) — Previous research has established that as social creatures, both humans and zebrafish (Danio rerio) turn to members of their species in the face of stress. This mitigation of stress response by social cues is a phenomenon called "social buffering." In humans, the neurotransmitter oxytocin plays a role in social buffering. A few studies suggest that oxytocin may also play a role in zebrafish social buffering, however, few studies have focused on this relationship.

My study intends to investigate the role of oxytocin in zebrafish social buffering. By administering an oxytocin inhibiting drug prior to stress exposure, behavioral markers of anxiety can be measured in isolated fish and in social condition fish who can see nearby fish. This project hopes to broaden our understanding of neural functioning across species.

"My summer research experience strengthened my confidence by pushing me to reach a new level of autonomy over the development of my project. I have no doubt that I am prepared for my endeavors after graduation because of this part of my mentorship and education."

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