Summer Research: Drosophila Insulin Signaling Pathway Research
Aviv Campbell '23 investigates the evolution and function of insulin signaling pathways in Drosophila species.
Allentown, PA (10/20/2022) — During the summer, Aviv Campbell '23 investigated the evolution and function of insulin signaling pathways in Drosophila species. To begin with, Campbell closely examined one or two genes within the insulin signaling pathway of multiple species of Drosophila, provided within the GEP browser. Campbell hopes to discover how the placement of a protein product, within the signaling pathway, affects its evolution. The hypothesis is that genes earlier in the pathway, or with less connections, will evolve faster. To test the hypothesis, Campbell will be identifying orthologs and their corresponding protein products. Campbell states that "this is essential to our project as this allows us to compare how target genes are constructed and what is resultantly encoded, within species." Finally, Campbell will note the presence and absence of genes within given genomes when observed.
"I learned more about who I am as a researcher and within a group work setting. In engaging with this research opportunity I was able to learn more about the process of evolution on a genetic scale and the evolution in how we conduct research on genetic processes."
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